Improvements in gel composition and electrophoretic conditions for broad-range mutation analysis by denaturing gradient gel electrophoresis.

Denaturing gradient gel electrophoresis (DGGE) is believed to be the most powerful pre-screening method for mutation detection currently available, being used mostly on an exon-by-exon basis. Broad-range DGGE for the analysis of multiple fragments or an entire gene is rarely applied. We and others h...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Hayes, V M, Wu, Y, Osinga, J, Mulder, I M, van der Vlies, P, Elfferich, P, Buys, C H, Hofstra, R M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1999
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10497279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.20.e29
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