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Presetting of chromatin structure and transcription factor binding poise the human GADD45 gene for rapid transcriptional up-regulation.

GADD45 has been suggested to coordinate cell cycle regulation with the repair of DNA damage following ionizing radiation (IR). Although the GADD45 gene is transcriptionally up-regulated in response to IR, alterations in in vivo transcription factor (TF) binding or chromatin structure associated with...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Principais autores: Graunke, D M, Fornace, A J, Pieper, R O
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148652/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10481028/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.19.3881
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