Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency.

Clinical applications of gene therapy mainly depend on the development of efficient gene transfer vectors. Large DNA molecules can only be transfected into cells by using synthetic vectors such as cationic lipids and polymers. The present investigation was therefore designed to explore the physicoch...

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Hlavní autoři: Kreiss, P, Cameron, B, Rangara, R, Mailhe, P, Aguerre-Charriol, O, Airiau, M, Scherman, D, Crouzet, J, Pitard, B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC148641/
https://ncbi.nlm.nih.gov/pubmed/10481017
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