Virus-sized self-assembling lamellar complexes between plasmid DNA and cationic micelles promote gene transfer

Gene therapy is based on the vectorization of genes to target cells and their subsequent expression. Cationic amphiphile-mediated delivery of plasmid DNA is the nonviral gene transfer method most often used. We examined the supramolecular structure of lipopolyamine/plasmid DNA complexes under variou...

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Dettagli Bibliografici
Autori principali: Pitard, Bruno, Aguerre, Olivier, Airiau, Marc, Lachagès, Anne-Marie, Boukhnikachvili, Tsiala, Byk, Gérardo, Dubertret, Catherine, Herviou, Christian, Scherman, Daniel, Mayaux, Jean-François, Crouzet, Joël
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25002/
https://ncbi.nlm.nih.gov/pubmed/9405626
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