Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts.

Mammalian mitochondria contain several 16.5 kb circular DNAs (mtDNA) encoding electron transport chain proteins. Reactive oxygen species formed as byproducts from oxidative phosphorylation in these organelles can cause oxidative deamination of cytosine and lead to uracil in mtDNA. Upon mtDNA replica...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Stierum, R H, Dianov, G L, Bohr, V A
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1999
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10471741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.18.3712
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