Aqueous trifluorethanol solutions simulate the environment of DNA in the crystalline state.

We took 28 fragments of DNA whose crystal structures were known and used CD spectroscopy to search for conditions stabilising the crystal structures in solution. All 28 fragments switched into their crystal structures in 60-80% aqueous trifluorethanol (TFE) to indicate that the crystals affected the...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Kypr, J, Chládková, J, Zimulová, M, Vorlícková, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10446234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.17.3466
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