Aqueous trifluorethanol solutions simulate the environment of DNA in the crystalline state.

We took 28 fragments of DNA whose crystal structures were known and used CD spectroscopy to search for conditions stabilising the crystal structures in solution. All 28 fragments switched into their crystal structures in 60-80% aqueous trifluorethanol (TFE) to indicate that the crystals affected the...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Kypr, J, Chládková, J, Zimulová, M, Vorlícková, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1999
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10446234/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.17.3466
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