Post-transcriptional regulation of the DNA damage-inducible gadd45 gene in human breast carcinoma cells exposed to a novel retinoid CD437.

The biologically active synthetic retinoid CD437 (6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene, AHPN) and different human breast carcinoma (HBC) cell lines were used to examine the possible mechanism(s) of gadd45 induction. Northern blot analysis of mRNA isolated from MCF-7, MDA-MB-468 and MDA-MB-2...

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Autori principali: Rishi, A K, Sun, R J, Gao, Y, Hsu, C K, Gerald, T M, Saeed Sheikh, M, Dawson, M I, Reichert, U, Shroot, B, Fornace, A J, Brewer, G, Fontana, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC148537/
https://ncbi.nlm.nih.gov/pubmed/10454607
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