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The Wilms' tumor suppressor gene (wt1) product represses different functional classes of transcriptional activation domains.

We have studied the ability of the wt1 tumor suppressor gene product to repress different classes of activation domains previously shown to stimulate the initiation and elongation steps of RNA polymerase II transcription in vivo. Repression assays revealed that WT1 represses all three classes of act...

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Autori principali: Lee, T H, Moffett, P, Pelletier, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC148503/
https://ncbi.nlm.nih.gov/pubmed/10390530
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