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The Dictyostelium LIM Domain-containing Protein LIM2 Is Essential for Proper Chemotaxis and Morphogenesis

We have identified limB, a gene encoding a novel LIM domain-containing protein, LIM2, in a screen for genes required for morphogenesis. limB null cells aggregate, although poorly, but they are unable to undergo morphogenesis, and the aggregates arrest at the mound stage. limB null cells exhibit an a...

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Detalhes bibliográficos
Main Authors: Chien, Sharon, Chung, Chang Y., Sukumaran, Sujatha, Osborne, Nicholas, Lee, Susan, Ellsworth, Charlene, McNally, James G., Firtel, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14846/
https://ncbi.nlm.nih.gov/pubmed/10749929
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