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Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein.

The N-terminus of human topoisomerase I participates in the binding of this enzyme to helicases and other proteins. Using the N-terminal 250 amino acids of human topoisomerase I and a yeast two-hybrid/ in vitro binding screen, a novel arginine-serine-rich peptide was identified as a human topoisomer...

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Autors principals: Haluska, P, Saleem, A, Rasheed, Z, Ahmed, F, Su, E W, Liu, L F, Rubin, E H
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC148458/
https://ncbi.nlm.nih.gov/pubmed/10352183
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