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Functional conformations of the L11–ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations

The interaction between the GTPase-associated center (GAC) and the aminoacyl-tRNA·EF-Tu·GTP ternary complex is of crucial importance in the dynamic process of decoding and tRNA accommodation. The GAC includes protein L11 and helices 43–44 of 23S rRNA (referred to as L11–rRNA complex). In this study,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Wen, Sengupta, Jayati, Rath, Bimal K., Frank, Joachim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484425/
https://ncbi.nlm.nih.gov/pubmed/16682558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2294806
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