Competitive inactivation of a double-strand DNA break site involves parallel suppression of meiosis-induced changes in chromatin configuration.

In Saccharomyces cerevisiae, DNA double-strand breaks (DSBs) initiate meiotic recombination at open sites in chromatin, which display a meiosis-specific increase in micrococcal nuclease (MNase) sensitivity. The arg4 promoter contains such a DSB site. When arg4 sequences are placed in a pBR322-derive...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Ohta, K, Wu, T C, Lichten, M, Shibata, T
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1999
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10219090/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.10.2175
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