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A Mutation in γ-Tubulin Alters Microtubule Dynamics and Organization and Is Synthetically Lethal with the Kinesin-like Protein Pkl1p

Mitotic segregation of chromosomes requires spindle pole functions for microtubule nucleation, minus end organization, and regulation of dynamics. γ-Tubulin is essential for nucleation, and we now extend its role to these latter processes. We have characterized a mutation in γ-tubulin that results i...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Paluh, Janet L., Nogales, Eva, Oakley, Berl R., McDonald, Kent, Pidoux, Alison L., Cande, W. Z.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10749926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.4.1225
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