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A Mutation in γ-Tubulin Alters Microtubule Dynamics and Organization and Is Synthetically Lethal with the Kinesin-like Protein Pkl1p

Mitotic segregation of chromosomes requires spindle pole functions for microtubule nucleation, minus end organization, and regulation of dynamics. γ-Tubulin is essential for nucleation, and we now extend its role to these latter processes. We have characterized a mutation in γ-tubulin that results i...

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Detalhes bibliográficos
Main Authors: Paluh, Janet L., Nogales, Eva, Oakley, Berl R., McDonald, Kent, Pidoux, Alison L., Cande, W. Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14843/
https://ncbi.nlm.nih.gov/pubmed/10749926
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