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Time-Lapse Video Microscopy Analysis Reveals Astral Microtubule Detachment in the Yeast Spindle Pole Mutant cnm67

Saccharomyces cerevisiae cnm67Δ cells lack the spindle pole body (SPB) outer plaque, the main attachment site for astral (cytoplasmic) microtubules, leading to frequent nuclear segregation failure. We monitored dynamics of green fluorescent protein–labeled nuclei and microtubules over several cell c...

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Auteurs principaux: Hoepfner, Dominic, Brachat, Arndt, Philippsen, Peter
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC14841/
https://ncbi.nlm.nih.gov/pubmed/10749924
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