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Saccharomyces cerevisiae Cells with Defective Spindle Pole Body Outer Plaques Accomplish Nuclear Migration via Half-Bridge–organized Microtubules

Cnm67p, a novel yeast protein, localizes to the microtubule organizing center, the spindle pole body (SPB). Deletion of CNM67 (YNL225c) frequently results in spindle misorientation and impaired nuclear migration, leading to the generation of bi- and multinucleated cells (40%). Electron microscopy in...

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Autors principals: Brachat, Arndt, Kilmartin, John V., Wach, Achim, Philippsen, Peter
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC25323/
https://ncbi.nlm.nih.gov/pubmed/9571234
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