DNA minor groove recognition by bis-benzimidazole analogues of Hoechst 33258: insights into structure-DNA affinity relationships assessed by fluorescence titration measurements.

Fluorescence titration measurements have been used to examine the binding interaction of a number of analogues of the bis -benzimidazole DNA minor groove binding agent Hoechst 33258 with the decamer duplex d(GCAAATTTGC)2. The method of continuous variation in ligand concentration (Job plot analysis)...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Bostock-Smith, C E, Searle, M S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1999
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10075992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.7.1619
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