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A base pair at the bottom of the anticodon stem is reciprocally preferred for discrimination of cognate tRNAs by Escherichia coli lysyl- and glutaminyl-tRNA synthetases

Although the yeast amber suppressor tRNA(Tyr) is a good candidate for a carrier of unnatural amino acids into proteins, slight misacylation with lysine was found to occur in an Escherichia coli protein synthesis system. Although it was possible to restrain the mislysylation by genetically engineerin...

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Detalhes bibliográficos
Main Authors: Fukunaga, Jun-ichi, Ohno, Satoshi, Nishikawa, Kazuya, Yokogawa, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483225/
https://ncbi.nlm.nih.gov/pubmed/16772402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl414
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