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Islet β cell failure in type 2 diabetes

The major focus of this Review is on the mechanisms of islet β cell failure in the pathogenesis of obesity-associated type 2 diabetes (T2D). As this demise occurs within the context of β cell compensation for insulin resistance, consideration is also given to the mechanisms involved in the compensat...

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Détails bibliographiques
Auteurs principaux: Prentki, Marc, Nolan, Christopher J.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483155/
https://ncbi.nlm.nih.gov/pubmed/16823478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29103
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