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Islet β cell failure in type 2 diabetes
The major focus of this Review is on the mechanisms of islet β cell failure in the pathogenesis of obesity-associated type 2 diabetes (T2D). As this demise occurs within the context of β cell compensation for insulin resistance, consideration is also given to the mechanisms involved in the compensat...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1483155/ https://ncbi.nlm.nih.gov/pubmed/16823478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29103 |
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