Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

OBJECTIVE: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes development remains poorly understood. The aim of this...

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Publicado en:Mol Metab
Autores principales: Motterle, Anna, Gattesco, Sonia, Peyot, Marie-Line, Esguerra, Jonathan Lou S., Gomez-Ruiz, Ana, Laybutt, D. Ross, Gilon, Patrick, Burdet, Frédéric, Ibberson, Mark, Eliasson, Lena, Prentki, Marc, Regazzi, Romano
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681241/
https://ncbi.nlm.nih.gov/pubmed/29107288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.08.005
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