Viscoelastic Study of the Mechanical Unfolding of a Protein by AFM

We have applied a dynamic force modulation technique to the mechanical unfolding of a homopolymer of immunoglobulin (Ig) domains from titin, (C47S C63S I27)(5), [(I27)(5)] to determine the viscoelastic response of single protein molecules as a function of extension. Both the stiffness and the fricti...

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Main Authors: Kawakami, Masaru, Byrne, Katherine, Brockwell, David J., Radford, Sheena E., Smith, D. Alastair
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biophysical Society 2006
Ábhair:
Biophysical Letters
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483103/
https://ncbi.nlm.nih.gov/pubmed/16698787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085019
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