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Yeast Gcn4p Stabilization Is Initiated by the Dissociation of the Nuclear Pho85p/Pcl5p Complex

Protein stability of the c-jun-like yeast bZIP transcriptional activator Gcn4p is exclusively controlled in the yeast nucleus. Phosphorylation by the nuclear Pho85p cyclin-dependent protein kinase, a functional homolog of mammalian Cdk5, initiates the Gcn4p degradation pathway in complex with the cy...

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Autors principals: Bömeke, Katrin, Pries, Ralph, Korte, Virginia, Scholz, Eva, Herzog, Britta, Schulze, Florian, Braus, Gerhard H.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483032/
https://ncbi.nlm.nih.gov/pubmed/16611745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0975
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