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Periodic Expression of the Cyclin-dependent Kinase Inhibitor p57(Kip2) in Trophoblast Giant Cells Defines a G2-like Gap Phase of the Endocycle

Endoreduplication is an unusual form of cell cycle in which rounds of DNA synthesis repeat in the absence of intervening mitoses. How G1/S cyclin-dependent kinase (Cdk) activity is regulated during the mammalian endocycle is poorly understood. We show here that expression of the G1/S Cdk inhibitor p...

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Bibliografiska uppgifter
Huvudupphovsmän: Hattori, Naka, Davies, Tyler C., Anson-Cartwright, Lynn, Cross, James C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC14829/
https://ncbi.nlm.nih.gov/pubmed/10712518
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