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Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
In mammalian cells, cyclin E–CDK2 complexes are activated in the late G(1) phase of the cell cycle and are believed to have an essential role in promoting S-phase entry. We have targeted the murine genes CCNE1 and CCNE2, encoding cyclins E1 and E2. Whereas single knockout mice were viable, double kn...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212738/ https://ncbi.nlm.nih.gov/pubmed/12970191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg482 |
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