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The salt dependence of DNA recognition by NF-kappaB p50: a detailed kinetic analysis of the effects on affinityand specificity.

The binding kinetics of NF-kappaB p50 to the Ig-kappaB site and to a DNA duplex with no specific binding site were determined under varying conditions of potassium chloride concentration using a surface plasmonresonance biosensor. Association and dissociation rate constants were measured enabling ca...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Hart, D J, Speight, R E, Cooper, M A, Sutherland, J D, Blackburn, J M
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148287/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.4.1063
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