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BINDING OF THE RESPIRATORY CHAIN INHIBITOR ANTIMYCIN TO THE MITOCHONDRIAL bc(1) COMPLEX: A NEW CRYSTAL STRUCTURE REVEALS AN ALTERED INTRAMOLECULAR HYDROGEN-BONDING PATTERN.
Antimycin A (antimycin), one of the first known and most potent inhibitors of the mitochondrial respiratory chain, binds to the quinone reduction site of the cytochrome bc(1) complex. Structure-activity-relationship studies have shown that the N-formylamino-salicylamide group is responsible for most...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482829/ https://ncbi.nlm.nih.gov/pubmed/16024040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2005.05.053 |
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