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Phosphorylation of Ser(158) regulates inflammatory redox-dependent hepatocyte nuclear factor-4α transcriptional activity

In IL-1β (interleukin 1β)-stimulated rat hepatocytes exposed to superoxide, we have previously identified an IRX (inflammatory redox)-sensitive DR1 [direct repeat of RG(G/T)TCA with one base spacing] cis-acting activator element (nt –1327 to –1315) in the iNOS (inducible nitric oxide synthase) promo...

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Autori principali: Guo, Hongtao, Gao, Chengjiang, Mi, Zhiyong, Wai, Philip Y., Kuo, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482807/
https://ncbi.nlm.nih.gov/pubmed/16351573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051730
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