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Atorvastatin prevents hypoxia-induced inhibition of endothelial nitric oxide synthase expression but does not affect heme oxygenase-1 in human microvascular endothelial cells

Beneficial cardiovascular effects of statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, are particularly assigned to the modulation of inflammation. Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) are listed among the crucial protective, anti-i...

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Autori principali: Loboda, Agnieszka, Jazwa, Agnieszka, Jozkowicz, Alicja, Dorosz, Jerzy, Balla, Jozsef, Molema, Grietje, Dulak, Jozef
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482780/
https://ncbi.nlm.nih.gov/pubmed/16620829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2006.03.015
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