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Effect of heme and heme oxygenase-1 on vascular endothelial growth factor synthesis and angiogenic potency of human keratinocytes

Background: Skin injury leads to the release of heme, a potent prooxidant which is degraded by heme oxygenase-1 (HO-1) to carbon monoxide, iron, and biliverdin, subsequently reduced to bilirubin. Recently the involvement of HO-1 in angiogenesis has been shown; however, the role of heme and HO-1 in w...

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Bibliographische Detailangaben
Hauptverfasser: Jazwa, Agnieszka, Loboda, Agnieszka, Golda, Slawomir, Cisowski, Jaroslaw, Szelag, Magdalena, Zagorska, Anna, Sroczynska, Patrycja, Drukala, Justyna, Jozkowicz, Alicja, Dulak, Jozef
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414644/
https://ncbi.nlm.nih.gov/pubmed/16545694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2005.11.016
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