Human DNA topoisomerase IIbeta binds and cleaves four-way junction DNA in vitro.
We have used gel retardation analysis to show that human DNA topoisomerase IIbeta can bind a 40 bp linear duplex containing a single DNA topoisomerase IIbeta cleavage site. Furthermore, we demonstrate for the first time that human DNA topoisomerase IIbeta binds to four-way junction DNA. This support...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1999
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.4.984 |
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