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SV40 Pseudovirion Gene Delivery of a Toxin to Treat Human Adenocarcinomas in Mice
SV40 vectors packaged in vitro (pseudovirions) are an efficient delivery system for plasmids up to 17.7 kb, with or without SV40 sequences. A truncated Pseudomonas exotoxin gene (PE38) was delivered into various human cells (HeLa, KB-3-1, human lymphoblastoids, and erythroleukemia cells) in vitro us...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482740/ https://ncbi.nlm.nih.gov/pubmed/16498428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cgt.7700943 |
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