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Multiple and time-scheduled in situ DNA delivery mediated by β-cyclodextrin embedded in a polyelectrolyte multilayer

The basic premise of gene therapy is that genes can be used to produce in situ therapeutic proteins. The controlled delivery of DNA complexes from biomaterials offers the potential to enhance gene transfer by maintaining an elevated concentration of DNA within the cellular microenvironment. Immobili...

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Autors principals: Jessel, N., Oulad-Abdelghani, M., Meyer, F., Lavalle, P., Haîkel, Y., Schaaf, P., Voegel, J.-C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482629/
https://ncbi.nlm.nih.gov/pubmed/16735471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508246103
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