Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films

Gene silencing by RNA interference (RNAi) has been shown to represent a recently discovered approach for the treatment of human diseases, including viral infection. A major limitation for the success of therapeutic strategies based on RNAi has been the delivery and shortlasting action of synthetic R...

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Autors principals: Dimitrova, Maria, Affolter, Christine, Meyer, Florent, Nguyen, Isabelle, Richard, Doriane G., Schuster, Catherine, Bartenschlager, Ralf, Voegel, Jean-Claude, Ogier, Joëlle, Baumert, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571015/
https://ncbi.nlm.nih.gov/pubmed/18922784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800156105
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