The plasma membrane permease PfNT1 is essential for purine salvage in the human malaria parasite Plasmodium falciparum

The human malaria parasite Plasmodium falciparum relies on the acquisition of host purines for its survival within human erythrocytes. Purine salvage by the parasite requires specialized transporters at the parasite plasma membrane (PPM), but the exact mechanism of purine entry into the infected ery...

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Bibliographic Details
Main Authors: El Bissati, Kamal, Zufferey, Rachel, Witola, William H., Carter, Nicola S., Ullman, Buddy, Ben Mamoun, Choukri
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482602/
https://ncbi.nlm.nih.gov/pubmed/16751273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602590103
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