PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation.

Overexpression of transcription factor AP-2 has been implicated in the tumorigenicity of the human teratocarcinoma cell lines PA-1 that contain an activated ras oncogene. Here we show evidence that overexpression of AP-2 sequesters transcriptional coactivators which results in self-inhibition. We id...

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Main Authors: Kannan, P, Yu, Y, Wankhade, S, Tainsky, M A
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148259/
https://ncbi.nlm.nih.gov/pubmed/9889285
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