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Observation of fragile-to-strong dynamic crossover in protein hydration water

At low temperatures, proteins exist in a glassy state, a state that has no conformational flexibility and shows no biological functions. In a hydrated protein, at temperatures ≳220 K, this flexibility is restored, and the protein is able to sample more conformational substates, thus becoming biologi...

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Bibliographic Details
Main Authors: Chen, S.-H., Liu, L., Fratini, E., Baglioni, P., Faraone, A., Mamontov, E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482557/
https://ncbi.nlm.nih.gov/pubmed/16751274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602474103
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