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Semirational design of Jun-Fos coiled coils with increased affinity: Universal implications for leucine zipper prediction and design
Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. For this reason, nine homologues of the AP-1 leucine zipper region have been characterized: Fos (c-Fos, FosB, Fra1, and Fra2), Jun (c-Jun, JunB, and JunD), and semirational library-designed winning peptides...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482553/ https://ncbi.nlm.nih.gov/pubmed/16754880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509880103 |
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