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Non-leucine residues in the leucine repeats of Fos and Jun contribute to the stability and determine the specificity of dimerization.

Various transcription factors, including C/EBP, GCN4 and members of the Fos, Jun and Myc families have been shown to form highly specific complexes via alpha-helical structures referred to as leucine zippers. Experimental evidence has suggested that dimerization involves the formation of hydrophobic...

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Hlavní autoři: Schuermann, M, Hunter, J B, Hennig, G, Müller, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC333705/
https://ncbi.nlm.nih.gov/pubmed/1901988
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