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Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms
The recent establishment of a robust hepatitis C virus (HCV) cell culture system permits analysis of virus-host interactions during HCV infection. Here, we report that HCV genotype 2a (JFH-1) infection fails to induce IFN-β or IFN-stimulated gene expression in Huh-7 cells, and that it blocks IFN-β a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482521/ https://ncbi.nlm.nih.gov/pubmed/16707574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602957103 |
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