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Thymic output in aged mice

Using GFP to mark recent thymic emigrants (RTEs) in mice carrying a GFP transgene driven by the recombination-activating gene 2 promoter, we demonstrate that RTEs are readily detectable even in 2-year-old mice, despite the fact that the proportion of the peripheral T cell pool comprised of RTEs decl...

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Bibliographic Details
Main Authors: Hale, J. Scott, Boursalian, Tamar E., Turk, Gail L., Fink, Pamela J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482512/
https://ncbi.nlm.nih.gov/pubmed/16717190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601040103
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