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Basic Fibroblast Growth Factor Inhibits the Anabolic Activity of Insulin-like Growth Factor 1 and Osteogenic Protein 1 in Adult Human Articular Chondrocytes
OBJECTIVE: To determine the effects of basic fibroblast growth factor (bFGF) on the chondrocyte anabolic activity promoted by insulin-like growth factor 1 (IGF-1) and osteogenic protein 1 (OP-1). METHODS: Human articular chondrocytes were cultured in alginate beads or as cartilage explants in serum-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482464/ https://ncbi.nlm.nih.gov/pubmed/16320338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.21472 |
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