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Basic Fibroblast Growth Factor Inhibits the Anabolic Activity of Insulin-like Growth Factor 1 and Osteogenic Protein 1 in Adult Human Articular Chondrocytes

OBJECTIVE: To determine the effects of basic fibroblast growth factor (bFGF) on the chondrocyte anabolic activity promoted by insulin-like growth factor 1 (IGF-1) and osteogenic protein 1 (OP-1). METHODS: Human articular chondrocytes were cultured in alginate beads or as cartilage explants in serum-...

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Hlavní autoři: Loeser, Richard F., Chubinskaya, Susan, Pacione, Carol, Im, Hee-Jeong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482464/
https://ncbi.nlm.nih.gov/pubmed/16320338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.21472
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