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Aging and Oxidative Stress Reduce the Response of Human Articular Chondrocytes to Insulin-Like Growth Factor-1 and Osteogenic Protein-1

OBJECTIVE: A reduced response of articular chondrocytes to growth factors with aging could contribute to the development of osteoarthritis. The purpose of this study was to determine the effects of aging and oxidative stress on the response of human articular chondrocytes to insulin-like growth fact...

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Bibliografiska uppgifter
Huvudupphovsmän: Loeser, Richard F., Gandhi, Uma, Long, David L., Yin, Weihong, Chubinskaya, Susan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116467/
https://ncbi.nlm.nih.gov/pubmed/24664641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38641
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