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Selection of an RNA domain that binds Zn2+.

We have selected an RNA that depends on zinc for affinity to a column, starting from a pool of ribooligonucleotides with 50 randomized positions. This RNA's chemical sensitivities, calculated folding thermodynamics, and activity when fragmented suggest that an ion binding site lies within a com...

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Bibliographic Details
Main Authors: Ciesiolka, J, Gorski, J, Yarus, M
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482428/
https://ncbi.nlm.nih.gov/pubmed/7489515
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