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Dual Lipid Modification Motifs in G(α) and G(γ) Subunits Are Required for Full Activity of the Pheromone Response Pathway in Saccharomyces cerevisiae

To establish the biological function of thioacylation (palmitoylation), we have studied the heterotrimeric guanine nucleotide–binding protein (G protein) subunits of the pheromone response pathway of Saccharomyces cerevisiae. The yeast G protein γ subunit (Ste18p) is unusual among G(γ) subunits beca...

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Udgivet i:Mol Biol Cell
Principais autores: Manahan, Carol L., Patnana, Madhavi, Blumer, Kendall J., Linder, Maurine E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10712512/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.3.957
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