Degradation of the Transcription Factor Gcn4 Requires the Kinase Pho85 and the SCF(CDC4) Ubiquitin–Ligase Complex
Gcn4, a yeast transcriptional activator that promotes the expression of amino acid and purine biosynthesis genes, is rapidly degraded in rich medium. Here we report that SCF(CDC4), a recently characterized protein complex that acts in conjunction with the ubiquitin-conjugating enzyme Cdc34 to degrad...
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| Vydáno v: | Mol Biol Cell |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Cell Biology
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10712509/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.3.915 |
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