The ability of the HIV-1 AAUAAA signal to bind polyadenylation factors is controlled by local RNA structure.
The 5' and 3' ends of HIV-1 transcripts are identical in sequence. This repeat region (R) folds a stem-loop structure that is termed the poly(A) hairpin because it contains polyadenylation or poly(A) signals: the AAUAAA hexamer motif, the cleavage site and part of the GU-rich downstream element. Obv...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9862964/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.2.446 |
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