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The ganglion-blocking activity of aminobicyclo[2,2,1]heptanes (congeners of mecamylamine) and bicyclo[3,2,1]azaoctanes (bridged congeners of pempidine)

The structural requirements for strong ganglion-blocking activity and long duration of action amongst some lower homologues of mecamylamine, together with the discovery of similar activities amongst isomers with enlarged ring structures, are described. In both series of compounds it was found that t...

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Détails bibliographiques
Auteurs principaux: Edge, N. D., Corne, S. J., Lee, G. E., Wragg, W. R.
Format: Artigo
Langue:Inglês
Publié: 1960
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481943/
https://ncbi.nlm.nih.gov/pubmed/19108133
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