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The ganglion-blocking activity of aminobicyclo[2,2,1]heptanes (congeners of mecamylamine) and bicyclo[3,2,1]azaoctanes (bridged congeners of pempidine)

The structural requirements for strong ganglion-blocking activity and long duration of action amongst some lower homologues of mecamylamine, together with the discovery of similar activities amongst isomers with enlarged ring structures, are described. In both series of compounds it was found that t...

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Detalhes bibliográficos
Main Authors: Edge, N. D., Corne, S. J., Lee, G. E., Wragg, W. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1960
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481943/
https://ncbi.nlm.nih.gov/pubmed/19108133
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