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Reversible inactivation of the transcriptional function of P53 protein by farnesylation
BACKGROUND: The use of integrating viral vectors in Gene therapy clinical trials has pointed out the problem of the deleterous effect of the integration of the ectopic gene to the cellular genome and the safety of this strategy. We proposed here a way to induce the death of gene modified cells upon...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1481662/ https://ncbi.nlm.nih.gov/pubmed/16732889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-6-26 |
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